Simultaneous Multi-city Kidney Swap Surgery Creates History

A multi-city kidney swap surgery in Toronto, Edmonton and Vancouver was conducted simultaneously as four patients suffering from severe kidney failure received new kidneys.

“It’s been challenging,” said Dr. Edward Cole, chair of the National Living Donor Kidney Exchange Program. “This is a real success story of people collaborating across the country, and with important input from Canadian Blood Services.”

Kidney swaps are basically based on the idea of group co-operation in which a donor whose kidney is not compatible with a loved one agrees to donate to a stranger, who also needs a new kidney. The first relative receives a new compatible kidney from another stranger in exchange.

Three donors in this surgery had offered to donate a kidney to a loved one, but were not a match. The fourth donor was an anonymous one. “This is an individual who came forward to donate not to someone they actually know on the waiting list, but had heard about the long waiting lists and the difficulty of living on dialysis,” said Dr. Sandra Cockfield, medical director of the renal transplant program at the University of Alberta.

In this case, all donors were put under general anesthesia and the surgery was only started when doctors said they were ready to begin on the recipients.

dialysis on wheels bangalore..costly

Dialysis At Your Doorstep

Dialysis At Your Doorstep

Mobile dialysis unit serves the dialysis needs of patients at their doorstep. Is it practical enough to survive? Sonal Shukla tries to find the answers

The idea of taking dialysis to patients rather than sick patients trudging to the hospital seems to have gained momentum in Indian healthcare. Only recently, the Mumbai Kidney Foundation in association with Naminathji Jain Foundation has furthered this cause by introducing a mobile dialysis unit (MDU) service in the limits of greater Mumbai. Mumbai’s PD Hinduja Hospital is also exploring the option of MDU service in the suburbs of Mumbai. For starters, the concept of MDU was first introduced in India by Bangalore’s Manipal Institute of Nephrology and Urology (MINU) in 2003.

A Need Indeed

A patient having permanent chronic dialysis has to visit the dialysis centre two to three times a week. For a paralysed or invalid person, going all the way to the dialysis centre is inconvenient. A dialysis van can reach him and the procedure can be performed either in the van or at his/her house. The concept of dialysis on wheels or MDU has thus taken root in cities like Bangalore and Mumbai. “A large number of our patients are elderly and people with physical disabilities. For this section of patients to come three times a week and spend four to six hours in the hospital for dialysis, wading through the chaotic traffic in Bangalore is difficult. Also, many of them do not have any family members who can accompany them and hence they were finding it extremely arduous to have dialysis,” explains Dr H Sudarshan Ballal, Director, MINU. Between its main centre and peripheral units, MINU conducts about 4,000 haemodialyses per month and 350-400 patients flock for haemodialysis and another 50 for peritoneal dialysis.

MDU is also a useful mode for dialysing people with acute renal failure in smaller hospitals and nursing homes where dialysis facilities are not available. According to Dr Umesh Khanna, Chairman of Mumbai Kidney Foundation, an MDU unit has a wider reach, catering to the genuine needs of the patients. For an acutely ill patient in the peripheral nursing homes with no facility of dialysis, the MDU provides a satisfactory option.

MDU is already an accepted phenomenon in developed counties like the US and the UK. However, the Indian healthcare industry only recently discovered the benefits of this concept, with Manipal Hospital taking the lead. “The logistics and the technical expertise were not available in India before. Also, the expenses involved in maintaining this unit for chronic haemodialysis has been the reason for the delay,” opines Dr Ballal. It costs more to run a mobile dialysis van, including critical care facility, than carrying out dialysis in the centre.

In Dr Khanna’s opinion, the fear in the minds of people as to whether dialysis can be done at home without the back-up support of the hospital is one major reason for the delay.

Clockwise: Mobile dialysis van service recently launched in Mumbai; A view of inside of the van

Functioning
‘Dialysis On Wheels’ of Manipal Hospital

The procedure for mobile dialysis is almost the same as dialysis centre, involving four hours. The MDU includes a vehicle equipped with all the machinery and accessories required to perform a standard haemodialysis. This includes dialysis machine, recliner, power backup, and a water tank with water purified through reverse osmosis (RO). It has a fully automated and remote controlled dialysis chair, which works like a dialysis bed and in addition there is a monitor deliberator and an artificial respirator.

It also carries accessories and equipment required to handle emergencies. “It has in-built life saving equipment and there is a senior dialysis technician and a dialysis doctor accompanying the mobile van, so it is an almost fully functional unit,” explains Dr Anil Suchak, President, Mumbai Kidney Foundation.

The investment for all these facilities is around Rs 20-25 lakh. “Our van has cost us around Rs 20 lakh including the infrastructure, air conditioning, installations, dialysis machine, dialysis chair, the ventilator and monitor,” says Dr Khanna.

Feasibility

Dr Bharat Shah, Consultant Nephrologist, Lilavati Hospital, Mumbai, believes, “MDU is double the cost of the centre unit because it needs more machine and manpower.” Are such facilities financially viable for hospitals? Industry experts believe that in the first few months, if the unit runs smoothly, then it can be very well accepted by the fraternity. Dr Alan Almeida, Consultant Nephrologist, Hinduja Hospital feels, as an MDU is an extension service where one is not providing dialysis within the hospital but also looking further, it should not be looked at from a profit angle by big hospitals but as a service to citizens.

“For the unit and the patient, the MDU should not be more than twice the cost of dialysis at the hospital. Initially, when done by an NGO the cost can be subsidised. But as it becomes popular, trusts which are already helping dialysis patients may come forward to help the MDU,” adds Dr Khanna.

If the benefits are multiple, why is this concept not gaining popularity? According to Dr Almeida, the concept will pick up well in a place where parking the MDU vehicle may not be difficult.

Experts hold that this concept can certainly be more popular in bigger cities and towns, but probably would take a much longer time to reach the rural masses. This is because it may not be cost-effective to provide dialysis in rural areas, unless there is significant contribution from the insurance companies or the Government healthcare to subsidise it. “Obviously, this will have to be a private public partnership with the Government, as most of the healthcare in rural India is still Government dependent. Unless we can work out the economical logistics of setting this up in the rural areas, it may take some time for this facility to reach them and the treatment cost would be a major barrier,” opines Dr Ballal. Manipal Hospital is already in dialogue with many smaller hospitals and nursing homes that do not have full-fledged nephrology and dialysis service to offer, especially to patients with acute renal failure.

Hinduja Hospital is considering the idea of an MDU which will mostly be operational in the suburban areas of the city. “It is a new concept and every new concept takes time to pick up. For the hospital, it will be like a further extension of the dialysis facility,” informs Dr Rasika Sirsat, Head of Nephrology, Hinduja Hospital.

Future Prospects

The success of this concept would depend on the demand. Given all the limitations of this concept, we must echo Dr VN Acharya, Former Head, Department of Nephrology, KEM Hospital, Mumbai: “Today we are talking about prevention of diseases, but what about patients who are already suffering from renal failure? MDU has been started as an experiment in Mumbai. Instead of criticising it, let us give it some time and let us see how we can go about it.”

ehm@expresshealthcaremgmt.com

Pathbreaking transplant at CMC

Pathbreaking transplant at CMC

V NarayanaMurthi
First Published : 18 Jun 2009 03:12:00 AM IST
Last Updated : 18 Jun 2009 08:12:47 AM IST

VELLORE: Kidney patients in India no longer have to lose heart if their blood groups do not match with those of the donor’s, for the Christian Medical College Hospital (CMCH) here successfully performed one such surgery recently.

A 21-year-old college student of Vellore with ‘O’ positive blood group received kidney from his mother, who is ‘A’ positive, to become the first person to have successfully undergone the first ever blood group incompatible kidney transplantation, claimed the hospital. Because his father, who runs a teashop, was a diabetic the mother was the only possible donor. With both kidneys failed the only other option he had was to survive on dialysis for the rest of his life.

Dr George T John, Head of Department of Nephrology, said till recently blood group compatibility was a basic requirement for successful transplantation and the new method introduced by the CMCH has crossed this barrier.

This has been made possible thanks to the advancement in technology and more potent immunosuppressive drugs, said his senior colleague Dr Chakko K Jacob. The new method avoided the removal of spleen, a usual practice in many of the advanced countries, as a standard procedure. Spleen is the organ which monitors the immune response system and activates antibodies to reject the transplanted organs. And in order to retain spleen, the CMCH team used a technique of plasmapheresis (plasma exchange), which removes part of the plasma in the blood of the recipient and substitutes the same from the blood bank
to ensure that it has no antibodies that can reject the transplanted kidney.

Dr Dolly Daniel, Head, Department of Transfusion Medicine, said that the crucial factor was to measure the antibodies that were responsible for the organ rejection. It took nearly one year for the CMCH to fine-tune the method to standardise the protocol, she added. Once done, the focus shifted to developing adaptive immunity on the part of the transplanted organ.

“The surgical procedures have also been simplified and it now takes less than three hours for a transplantation which has been made possible because of the coordination of specialists attached to different departments,” said Dr Nitin Kekre, Head, Department of Urology. The CMCH initiative has opened up the floodgates of hope for thousands of kidney patients as now they can opt for donors not necessarily belonging to their blood group. While this involves an additional expenditure of Rs 5 lakhs, it has been borne by the hospital for the first patient in the maiden venture.

First pig stem cells ‘to make humanised organs’

സൗജന്യ ഡയാലിസിസ്‌ യൂണിറ്റ്‌ വിപുലീകരണ ഉദ്‌ഘാടനം

Date : June 05 2009
സൗജന്യ ഡയാലിസിസ്‌ യൂണിറ്റ്‌ വിപുലീകരണ ഉദ്‌ഘാടനം

കോഴിക്കോട്‌:കോട്ടക്കല്‍ അല്‍മാസ്‌ സൂപ്പര്‍ സ്‌പെഷ്യാലിറ്റി ഹോസ്‌പിറ്റലിലെ സൗജന്യ ഡയാലിസിസ്‌ സെന്റര്‍ 23 യൂണിറ്റുകളായി വിപുലീകരിക്കുമെന്ന്‌ ഭാരവാഹികള്‍ പത്രസമ്മേളനത്തില്‍ അറിയിച്ചു. ഇതിന്റെ ഉദ്‌ഘാടനം ജൂണ്‍ ഏഴിന്‌ നാലുമണിക്ക്‌ കോഴിക്കോട്‌ മുജാഹിദ്‌ സെന്റര്‍ ന്യൂ ബ്ലോക്ക്‌ ഓഡിറ്റോറിയത്തില്‍ കളക്ടര്‍ പി.ബി. സലീം നിര്‍വഹിക്കും. കേരള നദ്‌വത്തുല്‍ മുജാഹിദീന്‍ ഉപഘടകമായ ഇന്റഗ്രേറ്റഡ്‌ മെഡിക്കല്‍ ബ്രദര്‍ഹുഡിന്റെ കീഴിലാണു അല്‍മാസ്‌ സൂപ്പര്‍ സ്‌പെഷ്യാലിറ്റി ഹോസ്‌പിറ്റല്‍ പ്രവര്‍ത്തിക്കുന്നത്‌.

കെ.എന്‍.എം. ജനറല്‍ സെക്രട്ടറി എ.പി. അബ്ദുല്‍ ഖാദിര്‍ മൗലവി, ട്രഷറര്‍ പാലത്ത്‌ അബ്ദുറഹ്‌മാന്‍ മദനി, കുഞ്ഞിമുഹമ്മദ്‌ മദനി പറപ്പൂര്‍, പ്രൊഫ. പി. അബ്ദു, ഡോ. സി. മുഹമ്മദ്‌, ഷാഹുല്‍ ഹമീദ്‌, സലിം ചാലിയം എന്നിവര്‍ പത്രസമ്മേളനത്തില്‍ പങ്കെടുത്തു.